Oxaprozin, also known as Oxaprozinum, (sold under the names: Daypro, Dayrun, Duraprox) is a non-steroidal anti-inflammatory drug (NSAID), used to relieve the inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis.
The reference site for Oxaprozin
WHAT IS Oxaprozin?
Oxaprozin is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Chemically, oxaprozin is a propionic acid derivative, and works by reducing hormones that cause inflammation and pain in the body.
Oxaprozin is used to reduce the pain, inflammation, and stiffness caused by rheumatoid arthritis, juvenile rheumatoid arthritis and osteoarthritis.
Brand Name(s): Caplets; Daypro
CAS nº: 21256-18-8
(ox a PROE zin)
The sections below will provide you with more specific information and guidelines related to oxaprozin and its correct use. Please read them carefully.
Oxaprozin was FDA-approved in October 1992. Following this, the potassium salt of oxaprozin received FDA approval in October 2002.
A prescription is required for this medicine.
Why is this medication prescribed?
Oxaprozin is used to reduce the pain, inflammation, and stiffness caused by rheumatoid arthritis, juvenile rheumatoid arthritis, and osteoarthritis.
This medication is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Chemically, oxaprozin is a propionic acid derivative, and it works by reducing hormones that cause inflammation and pain in the body.
Other uses for this medicine
Daypro® is sometimes used to treat Reiter’s Syndrome.
However, it is strongly advised that you consult your doctor or pharmacist for further information.
Dosage and using this medicine
Oxaprozin comes as a tablet to be taken orally. It is usually taken once or twice a day.
Take oxaprozin exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
Each dose should be taken with a full glass of water, and with food, milk, or an antacid to lessen stomach upsets.
Take oxaprozin at around the same time(s) each day.
What special precautions should I follow?
BEFORE TAKING OXAPROZIN:
Tell your doctor if you have an allergy to aspirin or any other NSAIDs, an ulcer or bleeding in your stomach, drink more than three alcoholic beverages a day, liver disease, kidney disease, a coagulation (bleeding) disorder, congestive heart failure, fluid retention, heart disease, or high blood pressure. You may not be able to take oxaprozin, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
Moreover, please inform your doctor if you are taking any of the following drugs: aspirin or another salicylate (form of aspirin) such as salsalate (Disalcid®), diflunisal (Dolobid®), choline salicylate-magnesium salicylate (Trilisate®, Tricosal®, others), and magnesium salicylate (Doan’s®, others); another nonsteroidal anti-inflammatory drug (NSAID) such as diclofenac (Cataflam®, Voltaren®), etodolac (Lodine®), fenoprofen (Nalfon®), flurbiprofen (Ansaid®), ibuprofen (Motrin®, Advil®, others), indomethacin (Indocin®), ketoprofen (Orudis®, Orudis KT®), ketorolac (Toradol®), meloxicam (Mobic®), nabumetone (Relafen®), naproxen (Aleve®, Anaprox®, Naprosyn®, Naprelan®, others), piroxicam (Feldene®), sulindac (Clinoril®), or tolmetin (Tolectin®); an over-the-counter cough, cold, allergy, or pain medicine that contains aspirin, ibuprofen, oxaprozin, or ketoprofen; an anticoagulant (blood thinner) such as warfarin (Coumadin®); a steroid such as prednisone (Deltasone®); insulin or an oral diabetes medicine such as glipizide (Glucotrol®), glyburide (Diabeta®, Micronase®), and others; probenecid (Benemid®); lithium (Eskalith®, Lithobid®, others); or bismuth subsalicylate in drugs such as Pepto-Bismol®. You may not be able to take oxaprozin, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.
Drugs other than those listed here may also interact with oxaprozin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.
Oxaprozin is in the FDA pregnancy category C. This means that it is not known whether oxaprozin will be harmful to an unborn baby. Oxaprozin should not be taken late in pregnancy (the third trimester) because a similar drug is known to affect the baby’s heart. Do not take oxaprozin without first talking to your doctor if you are pregnant or could become pregnant during treatment.
Additionally, it is not known whether this medication passes into breast milk. Do not take this medicine without first talking to your doctor if you are breast-feeding a baby.
Avoid prolonged exposure to sunlight. Oxaprozin may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.
Furthermore, avoid alcohol or use it with moderation. If you drink more than three alcoholic beverages a day, oxaprozin may increase the risk of dangerous stomach bleeding. Talk to your doctor before taking oxaprozin if you drink more than 3 alcoholic beverages a day.
What should I do if I forget a dose?
If you are taking oxaprozin on a regular schedule, take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Never take a double dose of this medication.
If you are taking oxaprozin as needed, take the missed dose if it is needed, then wait the recommended or prescribed amount of time before taking another dose.
What side effects can this medication cause?
Contact your doctor if you experience blood in vomit or bloody, black, or tarry stools. These symptoms could indicate damage to the stomach or intestines, which could be dangerous.
If you experience any of the following serious side effects, stop taking oxaprozin and seek medical treatment or contact your doctor immediately:
an allergic reaction (difficulty breathing, closing of the throat, swelling of the lips, tongue, or face, or hives)
muscle cramps, numbness, or tingling
ulcers (open sores) in the mouth
rapid weight gain (fluid retention)
decreased hearing or ringing in the ears
yellowing of your skin or eyes (jaundice)
abdominal cramping, heartburn, or indigestion
Other, less serious side effects may be more likely to occur. Continue to take oxaprozin and talk to your doctor if you experience:
dizziness or headache
nausea, diarrhea, or constipation
fatigue or weakness
irregular menstrual periods
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
What storage conditions are needed for this medicine?
Always keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
Remember to throw away any medication that is outdated or no longer needed. If you have any queries, please talk to your pharmacist about the proper disposal of your medication.
In case of an emergency/overdose
In the case of an overdose, call your local poison control center on 1-800-222-1222. However, if the victim has collapsed or is not breathing, please call the local emergency services immediately on 911.
Symptoms of overdose may include:
ringing in the ears
numbness or tingling
little or no urine production
PICTURES OF OXAPROZIN PILLS
Below you will find images and specific information on the principal types of oxaprozin that exist, including their respective brand name(s), strength, inscription codes, manufacturers and/or distributors.
The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.
Strength(s): 600 MG
Imprint: DAYPRO | 13 81
Distributors: PHYSICIANS TOTALCARE INC.
Strength(s): 600 MG
Imprint: G 5002
Manufacturer: GREENSTONE LTD.
Strength(s): 600 MG
Imprint: E 141
Manufacturer: EON LABS.
Strength(s): 600 MG
Imprint: 93 | 0924
Manufacturer: TEVA USA